6XOU

CryoEM structure of human presequence protease in open state

Summary for 6XOU

Entry DOI	10.2210/pdb6xou/pdb
EMDB information	22278 22279 22280 22281 22282
Descriptor	Presequence protease, mitochondrial (1 entity in total)
Functional Keywords	partial open state, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	114901.46
Authors	Liang, W.G.,Zhao, M.,Tang, W. (deposition date: 2020-07-07, release date: 2021-07-07, Last modification date: 2024-05-15)
Primary citation	Liang, W.G.,Wijaya, J.,Wei, H.,Noble, A.J.,Mancl, J.M.,Mo, S.,Lee, D.,Lin King, J.V.,Pan, M.,Liu, C.,Koehler, C.M.,Zhao, M.,Potter, C.S.,Carragher, B.,Li, S.,Tang, W.J. Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition. Nat Commun, 13:1833-1833, 2022 Cited by PubMed: 35383169 DOI: 10.1038/s41467-022-29322-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4 Å)

Structure validation