6XHF
Structure of Phenylalanyl-5'-O-adenosine phosphoramidate
Summary for 6XHF
Entry DOI | 10.2210/pdb6xhf/pdb |
Descriptor | Ribonuclease pancreatic, (2~{S})-2-[[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]amino]-3-phenyl-propanoic acid, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | rnase a complex, amino acid release, prodrug, rna binding protein |
Biological source | Bos taurus (Bovine) |
Total number of polymer chains | 2 |
Total formula weight | 28476.35 |
Authors | Pallan, P.S.,Egli, M. (deposition date: 2020-06-18, release date: 2021-03-17, Last modification date: 2023-10-18) |
Primary citation | Jovanovic, D.,Tremmel, P.,Pallan, P.S.,Egli, M.,Richert, C. The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid. Angew.Chem.Int.Ed.Engl., 59:20154-20160, 2020 Cited by PubMed: 32757352DOI: 10.1002/anie.202008665 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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