6XD5
Apo KPC-2 N170A mutant at 1.20 A
Summary for 6XD5
Entry DOI | 10.2210/pdb6xd5/pdb |
Descriptor | Carbapenem-hydrolyzing beta-lactamase KPC, GLYCEROL, SULFATE ION, ... (4 entities in total) |
Functional Keywords | carbapenemase, beta-lactamase, hydrolase |
Biological source | Klebsiella pneumoniae |
Total number of polymer chains | 1 |
Total formula weight | 31577.57 |
Authors | Pemberton, O.A.,Chen, Y. (deposition date: 2020-06-10, release date: 2020-12-09, Last modification date: 2023-10-18) |
Primary citation | Mehta, S.C.,Furey, I.M.,Pemberton, O.A.,Boragine, D.M.,Chen, Y.,Palzkill, T. KPC-2 beta-lactamase enables carbapenem antibiotic resistance through fast deacylation of the covalent intermediate. J.Biol.Chem., 296:100155-100155, 2020 Cited by PubMed: 33273017DOI: 10.1074/jbc.RA120.015050 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.2 Å) |
Structure validation
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