6XCS

Erythromycin esterase mutant EreC H289N in its open conformation

Summary for 6XCS

• Entry DOI: 10.2210/pdb6xcs/pdb
• Related: 6XCQ
• Descriptor: EreC (2 entities in total)
• Functional Keywords: macrolide, esterase, hydrolase
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 97837.05

Authors

Zielinski, M.,Berghuis, A.M. (deposition date: 2020-06-09, release date: 2021-02-17, Last modification date: 2023-11-15)

• Primary citation: Zielinski, M.,Park, J.,Sleno, B.,Berghuis, A.M.; Structural and functional insights into esterase-mediated macrolide resistance.; Nat Commun, 12:1732-1732, 2021; PubMed: 33741980; DOI: 10.1038/s41467-021-22016-3

Experimental method

X-RAY DIFFRACTION (2.4 Å)