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6XCM

Structure of the SARS-CoV-2 spike glycoprotein in complex with the C105 neutralizing antibody Fab fragment (state 1)

Summary for 6XCM
Entry DOI10.2210/pdb6xcm/pdb
EMDB information22127 22128
DescriptorSpike glycoprotein, C105 Fab Heavy Chain, C105 Fab Light Chain, ... (8 entities in total)
Functional Keywordssars-cov-2, spike glycoprotein, covid-19, monoclonal neutralizing antibody, fabs, nsempem, viral protein-immune system complex, viral protein/immune system
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
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Total number of polymer chains7
Total formula weight527029.15
Authors
Barnes, C.O.,Bjorkman, P.J. (deposition date: 2020-06-08, release date: 2020-07-01, Last modification date: 2020-09-02)
Primary citationBarnes, C.O.,West Jr., A.P.,Huey-Tubman, K.E.,Hoffmann, M.A.G.,Sharaf, N.G.,Hoffman, P.R.,Koranda, N.,Gristick, H.B.,Gaebler, C.,Muecksch, F.,Lorenzi, J.C.C.,Finkin, S.,Hagglof, T.,Hurley, A.,Millard, K.G.,Weisblum, Y.,Schmidt, F.,Hatziioannou, T.,Bieniasz, P.D.,Caskey, M.,Robbiani, D.F.,Nussenzweig, M.C.,Bjorkman, P.J.
Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies.
Cell, 182:828-, 2020
Cited by
PubMed: 32645326
DOI: 10.1016/j.cell.2020.06.025
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.42 Å)
Structure validation

217705

數據於2024-03-27公開中

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