6XCH
Room-temperature X-ray Crystal structure of SARS-CoV-2 main protease in complex with Leupeptin
Summary for 6XCH
Entry DOI | 10.2210/pdb6xch/pdb |
Descriptor | 3C-like proteinase, Leupeptin (3 entities in total) |
Functional Keywords | sars-cov-2 main protease, viral protein, hydrolase-inhibitor complex, hydrolase/inhibitor |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 2 |
Total formula weight | 34255.13 |
Authors | Kneller, D.W.,Kovalevsky, A.,Coates, L. (deposition date: 2020-06-08, release date: 2020-06-17, Last modification date: 2023-10-18) |
Primary citation | Kneller, D.W.,Galanie, S.,Phillips, G.,O'Neill, H.M.,Coates, L.,Kovalevsky, A. Malleability of the SARS-CoV-2 3CL M pro Active-Site Cavity Facilitates Binding of Clinical Antivirals. Structure, 28:1313-, 2020 Cited by PubMed: 33152262DOI: 10.1016/j.str.2020.10.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)