6X4L
PANK3 complex structure with compound PZ-3565
Summary for 6X4L
Entry DOI | 10.2210/pdb6x4l/pdb |
Descriptor | Pantothenate kinase 3, 1-[4-(5-chloropyrazin-2-yl)piperazin-1-yl]-2-[4-(propan-2-yl)phenyl]ethan-1-one, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (7 entities in total) |
Functional Keywords | pank, substrate, complex, transferase, pantothenate kinase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 43174.71 |
Authors | White, S.W.,Yun, M. (deposition date: 2020-05-22, release date: 2021-11-24, Last modification date: 2023-10-18) |
Primary citation | Sharma, L.K.,Yun, M.K.,Subramanian, C.,Tangallapally, R.,Jackowski, S.,Rock, C.O.,White, S.W.,Lee, R.E. LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators. Bioorg.Med.Chem., 52:116504-116504, 2021 Cited by PubMed: 34814071DOI: 10.1016/j.bmc.2021.116504 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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