6X37

Crystal structure of PT3245 bound to HIF2a-B*:ARNT-B* complex

Summary for 6X37

• Entry DOI: 10.2210/pdb6x37/pdb
• Descriptor: Endothelial PAS domain-containing protein 1, Aryl hydrocarbon receptor nuclear translocator, 3-fluoro-5-{[(7R)-7-hydroxy-1-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[c]pyridin-4-yl]oxy}benzonitrile, ... (4 entities in total)
• Functional Keywords: hif2a, pas b domain, arnt, hypoxia inducible factor, epas1, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 27532.05

Authors

Du, X. (deposition date: 2020-05-21, release date: 2021-05-26, Last modification date: 2023-10-18)

• Primary citation: Du, X.; Crystal structure of PT3245 bound to HIF2a-B*:ARNT-B* complex; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.94 Å)