6X25
CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 1-PHOSPHATASE INPP1 IN COMPLEX GADOLINIUM AFTER ADDITION OF INOSITOL 1,3,4-TRISPHOSPHATE AND LITHIUM AT 3.2 ANGSTROM RESOLUTION
Summary for 6X25
Entry DOI | 10.2210/pdb6x25/pdb |
Descriptor | Inositol polyphosphate 1-phosphatase, GADOLINIUM ATOM, SULFATE ION, ... (4 entities in total) |
Functional Keywords | inositol phosphate, neurological disease, bipolar disorder, manic depressive illness, phosphatase, signaling protein, lithium binding site |
Biological source | Bos taurus (Bovine) |
Total number of polymer chains | 1 |
Total formula weight | 44483.56 |
Authors | Dollins, D.E.,Endo-Streeter, S.,Ren, Y.,York, J.D. (deposition date: 2020-05-20, release date: 2020-11-25, Last modification date: 2023-10-18) |
Primary citation | Dollins, D.E.,Xiong, J.P.,Endo-Streeter, S.,Anderson, D.E.,Bansal, V.S.,Ponder, J.W.,Ren, Y.,York, J.D. A structural basis for lithium and substrate binding of an inositide phosphatase. J.Biol.Chem., 296:100059-100059, 2020 Cited by PubMed: 33172890DOI: 10.1074/jbc.RA120.014057 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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