6X25

CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 1-PHOSPHATASE INPP1 IN COMPLEX GADOLINIUM AFTER ADDITION OF INOSITOL 1,3,4-TRISPHOSPHATE AND LITHIUM AT 3.2 ANGSTROM RESOLUTION

Summary for 6X25

Entry DOI	10.2210/pdb6x25/pdb
Descriptor	Inositol polyphosphate 1-phosphatase, GADOLINIUM ATOM, SULFATE ION, ... (4 entities in total)
Functional Keywords	inositol phosphate, neurological disease, bipolar disorder, manic depressive illness, phosphatase, signaling protein, lithium binding site
Biological source	Bos taurus (Bovine)
Total number of polymer chains	1
Total formula weight	44483.56
Authors	Dollins, D.E.,Endo-Streeter, S.,Ren, Y.,York, J.D. (deposition date: 2020-05-20, release date: 2020-11-25, Last modification date: 2023-10-18)
Primary citation	Dollins, D.E.,Xiong, J.P.,Endo-Streeter, S.,Anderson, D.E.,Bansal, V.S.,Ponder, J.W.,Ren, Y.,York, J.D. A structural basis for lithium and substrate binding of an inositide phosphatase. J.Biol.Chem., 296:100059-100059, 2020 Cited by PubMed: 33172890 DOI: 10.1074/jbc.RA120.014057 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation