6X25

CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 1-PHOSPHATASE INPP1 IN COMPLEX GADOLINIUM AFTER ADDITION OF INOSITOL 1,3,4-TRISPHOSPHATE AND LITHIUM AT 3.2 ANGSTROM RESOLUTION

6X25 の概要

• エントリーDOI: 10.2210/pdb6x25/pdb
• 分子名称: Inositol polyphosphate 1-phosphatase, GADOLINIUM ATOM, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: inositol phosphate, neurological disease, bipolar disorder, manic depressive illness, phosphatase, signaling protein, lithium binding site
• 由来する生物種: Bos taurus (Bovine)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44483.56

構造登録者

Dollins, D.E.,Endo-Streeter, S.,Ren, Y.,York, J.D. (登録日: 2020-05-20, 公開日: 2020-11-25, 最終更新日: 2023-10-18)

• 主引用文献: Dollins, D.E.,Xiong, J.P.,Endo-Streeter, S.,Anderson, D.E.,Bansal, V.S.,Ponder, J.W.,Ren, Y.,York, J.D.; A structural basis for lithium and substrate binding of an inositide phosphatase.; J.Biol.Chem., 296:100059-100059, 2020; PubMed: 33172890; DOI: 10.1074/jbc.RA120.014057

実験手法

X-RAY DIFFRACTION (3.2 Å)