6X19
Non peptide agonist CHU-128, bound to Glucagon-Like peptide-1 (GLP-1) Receptor
Summary for 6X19
Entry DOI | 10.2210/pdb6x19/pdb |
Related | 6X18 |
EMDB information | 21992 21993 21994 |
Descriptor | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total) |
Functional Keywords | g-coupled protein receptor, gpcr, membrane protein, non-peptide agonist |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 5 |
Total formula weight | 160992.44 |
Authors | Belousoff, M.J.,Zhang, X.,Danev, R. (deposition date: 2020-05-18, release date: 2020-09-09, Last modification date: 2020-11-18) |
Primary citation | Zhang, X.,Belousoff, M.J.,Zhao, P.,Kooistra, A.J.,Truong, T.T.,Ang, S.Y.,Underwood, C.R.,Egebjerg, T.,Senel, P.,Stewart, G.D.,Liang, Y.L.,Glukhova, A.,Venugopal, H.,Christopoulos, A.,Furness, S.G.B.,Miller, L.J.,Reedtz-Runge, S.,Langmead, C.J.,Gloriam, D.E.,Danev, R.,Sexton, P.M.,Wootten, D. Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists. Mol.Cell, 80:485-, 2020 Cited by PubMed: 33027691DOI: 10.1016/j.molcel.2020.09.020 PDB entries with the same primary citation |
Experimental method |
Structure validation
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