6X0T

Structure of human plasma factor XIIa in complex with (2S)-1-(N,3-dicyclohexyl-D-alanyl)-4-[(4R,5S)-4-methyl-5-phenyl-4,5-dihydro-1,3-oxazol-2-yl]-N-[(thiophen-2-yl)methyl]piperazine-2-carboxamide (compound 8h)

6X0T の概要

• エントリーDOI: 10.2210/pdb6x0t/pdb
• 分子名称: Coagulation factor XII, (2S)-1-(N,3-dicyclohexyl-D-alanyl)-4-[(4R,5S)-4-methyl-5-phenyl-4,5-dihydro-1,3-oxazol-2-yl]-N-[(thiophen-2-yl)methyl]piperazine-2-carboxamide, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: protease, blood clotting, inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 85765.35

構造登録者

Orth, P. (登録日: 2020-05-17, 公開日: 2021-05-19, 最終更新日: 2023-10-18)

• 主引用文献: Rao, A.U.,Chu, H.D.; Structure of human plasma factor XIIa in complex with (2S)-1-(N,3-dicyclohexyl-D-alanyl)-4-[(4R,5S)-4-methyl-5-phenyl-4,5-dihydro-1,3-oxazol-2-yl]-N-[(thiophen-2-yl)methyl]piperazine-2-carboxamide (compound 8h); To Be Published,

実験手法

X-RAY DIFFRACTION (1.388 Å)