6X0S

Structure of human plasma factor XIIa in complex with (2S)-4-(5-chloro-1,3-benzoxazol-2-yl)-1-(N,3-dicyclohexyl-D-alanyl)-N-[(thiophen-2-yl)methyl]piperazine-2-carboxamide (compound 7)

6X0S の概要

• エントリーDOI: 10.2210/pdb6x0s/pdb
• 分子名称: Coagulation factor XII, (2S)-4-(5-chloro-1,3-benzoxazol-2-yl)-1-(N,3-dicyclohexyl-D-alanyl)-N-[(thiophen-2-yl)methyl]piperazine-2-carboxamide, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: preotease, blood clotting, inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 85742.44

構造登録者

Orth, P. (登録日: 2020-05-17, 公開日: 2021-05-19, 最終更新日: 2023-10-18)

• 主引用文献: Rao, A.U.,Chu, H.D.; Structure of human plasma factor XIIa in complex with (2S)-4-(5-chloro-1,3-benzoxazol-2-yl)-1-(N,3-dicyclohexyl-D-alanyl)-N-[(thiophen-2-yl)methyl]piperazine-2-carboxamide (compound 7); To Be Published,

実験手法

X-RAY DIFFRACTION (1.898 Å)