6X01

Crystal structure of the GltPh V216C-A391C mutant cross-linked in outward-facing state

Summary for 6X01

• Entry DOI: 10.2210/pdb6x01/pdb
• Descriptor: Glutamate transporter homolog, ASPARTIC ACID, SODIUM ION (3 entities in total)
• Functional Keywords: glutamate transporter homolog, transport protein
• Biological source: Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
• Total number of polymer chains: 3
• Total formula weight: 134292.35

Authors

Chen, I.,Font, J.,Ryan, R. (deposition date: 2020-05-15, release date: 2021-02-17, Last modification date: 2023-10-18)

• Primary citation: Chen, I.,Pant, S.,Wu, Q.,Cater, R.J.,Sobti, M.,Vandenberg, R.J.,Stewart, A.G.,Tajkhorshid, E.,Font, J.,Ryan, R.M.; Glutamate transporters have a chloride channel with two hydrophobic gates.; Nature, 591:327-331, 2021; PubMed: 33597752; DOI: 10.1038/s41586-021-03240-9

Experimental method

X-RAY DIFFRACTION (3.65 Å)