6WYS

Lon protease proteolytic domain

Summary for 6WYS

Entry DOI	10.2210/pdb6wys/pdb
Descriptor	Lon protease homolog, mitochondrial, SULFATE ION (3 entities in total)
Functional Keywords	proteolytic domain, hydrolase
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	71844.98
Authors	Lee, C.C.,Spraggon, G. (deposition date: 2020-05-13, release date: 2021-04-14, Last modification date: 2023-10-18)
Primary citation	Kingsley, L.J.,He, X.,McNeill, M.,Nelson, J.,Nikulin, V.,Ma, Z.,Lu, W.,Zhou, V.W.,Manuia, M.,Kreusch, A.,Gao, M.Y.,Witmer, D.,Vaillancourt, M.T.,Lu, M.,Greenblatt, S.,Lee, C.,Vashisht, A.,Bender, S.,Spraggon, G.,Michellys, P.Y.,Jia, Y.,Haling, J.R.,Lelais, G. Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology. J.Med.Chem., 64:4857-4869, 2021 Cited by PubMed: 33821636 DOI: 10.1021/acs.jmedchem.0c02152 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.229 Å)

Structure validation