6WYB

RTX (Reverse Transcription Xenopolymerase) in complex with an RNA/DNA hybrid

Summary for 6WYB

Entry DOI	10.2210/pdb6wyb/pdb
Descriptor	DNA polymerase, RNA strand, DNA strand, ... (7 entities in total)
Functional Keywords	reverse transcription, proofreading, 3' to 5' exonuclease, thumb, rtx, kod, reverse tanscription xenopolymerase, replication, rna, dna, transferase-rna-dna complex, transferase/rna/dna
Biological source	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) More
Total number of polymer chains	3
Total formula weight	99696.83
Authors	Choi, W.S.,He, P.,Pothukuchy, A.,Gollihar, J.,Ellington, A.D.,Yang, W. (deposition date: 2020-05-12, release date: 2020-08-19, Last modification date: 2023-10-18)
Primary citation	Choi, W.S.,He, P.,Pothukuchy, A.,Gollihar, J.,Ellington, A.D.,Yang, W. How a B family DNA polymerase has been evolved to copy RNA. Proc.Natl.Acad.Sci.USA, 117:21274-21280, 2020 Cited by PubMed: 32817521 DOI: 10.1073/pnas.2009415117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation