6WYB

RTX (Reverse Transcription Xenopolymerase) in complex with an RNA/DNA hybrid

6WYB の概要

• エントリーDOI: 10.2210/pdb6wyb/pdb
• 分子名称: DNA polymerase, RNA strand, DNA strand, ... (7 entities in total)
• 機能のキーワード: reverse transcription, proofreading, 3' to 5' exonuclease, thumb, rtx, kod, reverse tanscription xenopolymerase, replication, rna, dna, transferase-rna-dna complex, transferase/rna/dna
• 由来する生物種: Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 99696.83

構造登録者

Choi, W.S.,He, P.,Pothukuchy, A.,Gollihar, J.,Ellington, A.D.,Yang, W. (登録日: 2020-05-12, 公開日: 2020-08-19, 最終更新日: 2023-10-18)

• 主引用文献: Choi, W.S.,He, P.,Pothukuchy, A.,Gollihar, J.,Ellington, A.D.,Yang, W.; How a B family DNA polymerase has been evolved to copy RNA.; Proc.Natl.Acad.Sci.USA, 117:21274-21280, 2020; PubMed: 32817521; DOI: 10.1073/pnas.2009415117

実験手法

X-RAY DIFFRACTION (2.5 Å)