6WY1

Crystal structure of an engineered thermostable dengue virus 2 envelope protein dimer

6WY1 の概要

• エントリーDOI: 10.2210/pdb6wy1/pdb
• 分子名称: Dengue 2 soluble recombinant envelope, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• 機能のキーワード: dengue virus, envelope protein, thermostable, computational protein design, protein engineering, viral protein
• 由来する生物種: Dengue virus 2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45915.53

構造登録者

Kudlacek, S.T.,Lakshmanane, P.,Kuhlman, B. (登録日: 2020-05-12, 公開日: 2021-11-10, 最終更新日: 2023-10-18)

• 主引用文献: Kudlacek, S.T.,Metz, S.,Thiono, D.,Payne, A.M.,Phan, T.T.N.,Tian, S.,Forsberg, L.J.,Maguire, J.,Seim, I.,Zhang, S.,Tripathy, A.,Harrison, J.,Nicely, N.I.,Soman, S.,McCracken, M.K.,Gromowski, G.D.,Jarman, R.G.,Premkumar, L.,de Silva, A.M.,Kuhlman, B.; Designed, highly expressing, thermostable dengue virus 2 envelope protein dimers elicit quaternary epitope antibodies.; Sci Adv, 7:eabg4084-eabg4084, 2021; PubMed: 34652943; DOI: 10.1126/sciadv.abg4084

実験手法

X-RAY DIFFRACTION (3.42 Å)