6WX2

Vaccine-elicited mouse FP-targeting neutralizing antibody vFP16.02 with F60P mutation on light chain in complex with HIV fusion peptide (residue 512-519)

6WX2 の概要

• エントリーDOI: 10.2210/pdb6wx2/pdb
• 分子名称: vFP16.02 antibody heavy chain, vFP16.02 antibody light chain, fusion peptide, ... (4 entities in total)
• 機能のキーワード: hiv, fusion peptide, antibody, immune system-viral protein complex, immune system/viral protein
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 95788.78

構造登録者

Xu, K.,Wang, Y.,Kwong, P.D. (登録日: 2020-05-09, 公開日: 2021-03-17, 最終更新日: 2023-10-18)

• 主引用文献: Madan, B.,Zhang, B.,Xu, K.,Chao, C.W.,O'Dell, S.,Wolfe, J.R.,Chuang, G.Y.,Fahad, A.S.,Geng, H.,Kong, R.,Louder, M.K.,Nguyen, T.D.,Rawi, R.,Schon, A.,Sheng, Z.,Nimrania, R.,Wang, Y.,Zhou, T.,Lin, B.C.,Doria-Rose, N.A.,Shapiro, L.,Kwong, P.D.,DeKosky, B.J.; Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 33649208; DOI: 10.1073/pnas.2011653118

実験手法

X-RAY DIFFRACTION (2.39 Å)