Summary for 6WUP
| Entry DOI | 10.2210/pdb6wup/pdb |
| Descriptor | Ancestral cyclohexadienyl dehydratase, AncCDT-5, CHLORIDE ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total) |
| Functional Keywords | cyclohexadienyl dehydratase ancestral protein reconstruction, lyase |
| Biological source | synthetic construct |
| Total number of polymer chains | 1 |
| Total formula weight | 27240.27 |
| Authors | Kaczmarski, J.A.,Mahawaththa, M.C. (deposition date: 2020-05-05, release date: 2020-05-13, Last modification date: 2023-10-18) |
| Primary citation | Kaczmarski, J.A.,Mahawaththa, M.C.,Feintuch, A.,Clifton, B.E.,Adams, L.A.,Goldfarb, D.,Otting, G.,Jackson, C.J. Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme. Nat Commun, 11:5945-5945, 2020 Cited by PubMed: 33230119DOI: 10.1038/s41467-020-19695-9 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.49 Å) |
Structure validation
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