6WRV

Crystal structure of computationally designed protein 3DS18 in complex with the human Transferrin receptor ectodomain

6WRV の概要

• エントリーDOI: 10.2210/pdb6wrv/pdb
• 分子名称: Transferrin receptor protein 1, Computationally designed protein 3DS18, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: complex, beta sheet, receptor, de novo protein, de novo protein-metal transport complex, de novo protein/metal transport
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 253314.24

構造登録者

Abraham, J.,Baker, D.,Sahtoe, D.D.,Coscia, A.,Clark, L.,Olal, D. (登録日: 2020-04-30, 公開日: 2021-04-28, 最終更新日: 2023-10-18)

• 主引用文献: Sahtoe, D.D.,Coscia, A.,Mustafaoglu, N.,Miller, L.M.,Olal, D.,Vulovic, I.,Yu, T.Y.,Goreshnik, I.,Lin, Y.R.,Clark, L.,Busch, F.,Stewart, L.,Wysocki, V.H.,Ingber, D.E.,Abraham, J.,Baker, D.; Transferrin receptor targeting by de novo sheet extension.; Proc.Natl.Acad.Sci.USA, 118:-, 2021; PubMed: 33879614; DOI: 10.1073/pnas.2021569118

実験手法

X-RAY DIFFRACTION (2.47 Å)