6WPS

Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment

6WPS の概要

• エントリーDOI: 10.2210/pdb6wps/pdb
• EMDBエントリー: 21864 21865
• 分子名称: spike glycoprotein, S309 neutralizing antibody heavy chain, S309 neutralizing antibody light chain, ... (6 entities in total)
• 機能のキーワード: sars-cov-2, sars-cov, spike glycoprotein, fusion protein, neutralizing antibody, sarbecovirus, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 516512.57

構造登録者

Pinto, D.,Park, Y.J.,Beltramello, M.,Walls, A.C.,Tortorici, M.A.,Bianchi, S.,Jaconi, S.,Culap, K.,Zatta, F.,De Marco, A.,Peter, A.,Guarino, B.,Spreafico, R.,Cameroni, E.,Case, J.B.,Chen, R.E.,Havenar-Daughton, C.,Snell, G.,Virgin, H.W.,Lanzavecchia, A.,Diamond, M.S.,Fink, K.,Veesler, D.,Corti, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2020-04-27, 公開日: 2020-05-27, 最終更新日: 2021-05-19)

• 主引用文献: Pinto, D.,Park, Y.J.,Beltramello, M.,Walls, A.C.,Tortorici, M.A.,Bianchi, S.,Jaconi, S.,Culap, K.,Zatta, F.,De Marco, A.,Peter, A.,Guarino, B.,Spreafico, R.,Cameroni, E.,Case, J.B.,Chen, R.E.,Havenar-Daughton, C.,Snell, G.,Telenti, A.,Virgin, H.W.,Lanzavecchia, A.,Diamond, M.S.,Fink, K.,Veesler, D.,Corti, D.; Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody.; Nature, 583:290-295, 2020; PubMed: 32422645; DOI: 10.1038/s41586-020-2349-y

実験手法

ELECTRON MICROSCOPY (3.1 Å)