6WP6
Pyruvate Kinase M2 mutant-S37E K433E
Summary for 6WP6
Entry DOI | 10.2210/pdb6wp6/pdb |
Descriptor | Pyruvate kinase PKM, NITRATE ION, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | glycolysis, gene regulation, phosphotransferase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 120659.06 |
Authors | Nandi, S.,Razzaghi, M.,Srivastava, D.,Dey, M. (deposition date: 2020-04-26, release date: 2020-10-07, Last modification date: 2023-10-18) |
Primary citation | Nandi, S.,Razzaghi, M.,Srivastava, D.,Dey, M. Structural basis for allosteric regulation of pyruvate kinase M2 by phosphorylation and acetylation. J.Biol.Chem., 295:17425-17440, 2020 Cited by PubMed: 33453989DOI: 10.1074/jbc.RA120.015800 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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