6WOG
Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 5-methylenebisphosphonate inositol pentakisphosphate (5-PCP-IP5)
Summary for 6WOG
Entry DOI | 10.2210/pdb6wog/pdb |
Descriptor | Diphosphoinositol polyphosphate phosphohydrolase 1, Methylenebisphosphonate inositol pentakisphosphate, SULFATE ION, ... (4 entities in total) |
Functional Keywords | phosphatase, nudix, catalysis mechanism, substrate specificity, inositol, inositol pyrophosphate, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 20377.03 |
Authors | Zong, G.N.,Wang, H.C.,Shears, S.B. (deposition date: 2020-04-24, release date: 2021-03-03, Last modification date: 2024-03-06) |
Primary citation | Zong, G.,Jork, N.,Hostachy, S.,Fiedler, D.,Jessen, H.J.,Shears, S.B.,Wang, H. New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1. Faseb J., 35:e21275-e21275, 2021 Cited by PubMed: 33475202DOI: 10.1096/fj.202001489R PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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