6WMM

Human poly-N-acetyl-lactosamine synthase structure demonstrates a modular assembly of catalytic subsites for GT-A glycosyltransferases

6WMM の概要

• エントリーDOI: 10.2210/pdb6wmm/pdb
• 分子名称: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... (8 entities in total)
• 機能のキーワード: glycosyltransferase, gt-a fold, poly lacnac synthesis, transferase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 88262.53

構造登録者

Kadirvelraj, R.,Wood, Z.A. (登録日: 2020-04-21, 公開日: 2020-12-02, 最終更新日: 2021-04-28)

• 主引用文献: Kadirvelraj, R.,Yang, J.Y.,Kim, H.W.,Sanders, J.H.,Moremen, K.W.,Wood, Z.A.; Comparison of human poly-N-acetyl-lactosamine synthase structure with GT-A fold glycosyltransferases supports a modular assembly of catalytic subsites.; J.Biol.Chem., 296:100110-100110, 2020; PubMed: 33229435; DOI: 10.1074/jbc.RA120.015305

実験手法

X-RAY DIFFRACTION (1.548 Å)