6WMI

ZNF410 zinc fingers 1-5 with 17 mer blunt DNA Oligonucleotide

Summary for 6WMI

• Entry DOI: 10.2210/pdb6wmi/pdb
• Descriptor: Zinc finger protein 410, DNA (5'-D(*CP*AP*CP*AP*TP*CP*CP*CP*AP*TP*AP*AP*TP*AP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*TP*AP*TP*GP*GP*GP*AP*TP*GP*TP*G)-3'), ... (6 entities in total)
• Functional Keywords: transcription factor, zinc finger, complex, dna, transcription, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 56914.67

Authors

Ren, R.,Horton, J.R.,Cheng, X. (deposition date: 2020-04-21, release date: 2020-12-09, Last modification date: 2024-03-06)

• Primary citation: Lan, X.,Ren, R.,Feng, R.,Ly, L.C.,Lan, Y.,Zhang, Z.,Aboreden, N.,Qin, K.,Horton, J.R.,Grevet, J.D.,Mayuranathan, T.,Abdulmalik, O.,Keller, C.A.,Giardine, B.,Hardison, R.C.,Crossley, M.,Weiss, M.J.,Cheng, X.,Shi, J.,Blobel, G.A.; ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression.; Mol.Cell, 81:239-254.e8, 2021; PubMed: 33301730; DOI: 10.1016/j.molcel.2020.11.006

Experimental method

X-RAY DIFFRACTION (2.75 Å)