6WKP

Crystal structure of RNA-binding domain of nucleocapsid phosphoprotein from SARS CoV-2, monoclinic crystal form

6WKP の概要

• エントリーDOI: 10.2210/pdb6wkp/pdb
• 分子名称: Nucleoprotein, ZINC ION, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: csgid, covid-19, sars cov-2, rna-binding domain, nucleocapsid protein, nucleoprotein, structural genomics, center for structural genomics of infectious diseases, viral protein, rna binding protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 57063.23

構造登録者

Chang, C.,Michalska, K.,Jedrzejczak, R.,Maltseva, N.,Endres, M.,Godzik, A.,Kim, Y.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2020-04-16, 公開日: 2020-04-29, 最終更新日: 2024-02-28)

• 主引用文献: Kim, Y.,Maltseva, N.,Tesar, C.,Jedrzejczak, R.,Endres, M.,Ma, H.,Dugan, H.L.,Stamper, C.T.,Chang, C.,Li, L.,Changrob, S.,Zheng, N.Y.,Huang, M.,Ramanathan, A.,Wilson, P.,Michalska, K.,Joachimiak, A.; Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.; Iscience, 27:108976-108976, 2024; PubMed: 38327783; DOI: 10.1016/j.isci.2024.108976

実験手法

X-RAY DIFFRACTION (2.67 Å)