6WFQ
NanR dimer-DNA hetero-complex
Summary for 6WFQ
Entry DOI | 10.2210/pdb6wfq/pdb |
EMDB information | 21652 |
Descriptor | HTH-type transcriptional repressor NanR, DNA (5'-D(P*GP*GP*TP*AP*TP*AP*AP*CP*AP*GP*GP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*CP*CP*TP*GP*TP*TP*AP*TP*AP*CP*C)-3') (3 entities in total) |
Functional Keywords | nanr dimer-dna hetero-complex, transcriptional regulator, gntr superfamily, sialic acid, neu5ac, cooperativity., gene regulation |
Biological source | Escherichia coli More |
Total number of polymer chains | 4 |
Total formula weight | 68308.73 |
Authors | Hariprasad, V.,Horne, C.,Santosh, P.,Amy, H.,Emre, B.,Rachel, N.,Michael, G.,Georg, R.,Borries, D.,Renwick, D. (deposition date: 2020-04-03, release date: 2021-03-10, Last modification date: 2024-03-06) |
Primary citation | Horne, C.R.,Venugopal, H.,Panjikar, S.,Wood, D.M.,Henrickson, A.,Brookes, E.,North, R.A.,Murphy, J.M.,Friemann, R.,Griffin, M.D.W.,Ramm, G.,Demeler, B.,Dobson, R.C.J. Mechanism of NanR gene repression and allosteric induction of bacterial sialic acid metabolism. Nat Commun, 12:1988-1988, 2021 Cited by PubMed: 33790291DOI: 10.1038/s41467-021-22253-6 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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