6WEU

Crystal structures of human E-NPP 1: bound to adenosine-5'-thio-monophosphate

これはPDB形式変換不可エントリーです。

6WEU の概要

• エントリーDOI: 10.2210/pdb6weu/pdb
• 分子名称: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: human e-npp 1; drug discovery; inhibitors, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 214295.02

構造登録者

Peat, T.S.,Dennis, M.,Newman, J. (登録日: 2020-04-03, 公開日: 2020-09-09, 最終更新日: 2023-10-18)

• 主引用文献: Dennis, M.L.,Newman, J.,Dolezal, O.,Hattarki, M.,Surjadi, R.N.,Nuttall, S.D.,Pham, T.,Nebl, T.,Camerino, M.,Khoo, P.S.,Monahan, B.J.,Peat, T.S.; Crystal structures of human ENPP1 in apo and bound forms.; Acta Crystallogr D Struct Biol, 76:889-898, 2020; PubMed: 32876064; DOI: 10.1107/S2059798320010505

実験手法

X-RAY DIFFRACTION (2.65 Å)