6WDX
Crystal Structure of Danio rerio Histone Deacetylase 10 in Complex with Hydroxyethylindole Phenylhydroxamate Inhibitor
Summary for 6WDX
Entry DOI | 10.2210/pdb6wdx/pdb |
Descriptor | Polyamine deacetylase HDAC10, N-hydroxy-4-{[3-(2-hydroxyethyl)-1H-indol-1-yl]methyl}benzamide, ZINC ION, ... (6 entities in total) |
Functional Keywords | histone deacetylase, hydolase-hydrolase inhibitor complex, hydolase/hydrolase inhibitor |
Biological source | Danio rerio (Zebrafish) |
Total number of polymer chains | 1 |
Total formula weight | 75794.51 |
Authors | Herbst-Gervasoni, C.J.,Christianson, D.W. (deposition date: 2020-04-01, release date: 2020-07-22, Last modification date: 2023-10-18) |
Primary citation | Herbst-Gervasoni, C.J.,Steimbach, R.R.,Morgen, M.,Miller, A.K.,Christianson, D.W. Structural Basis for the Selective Inhibition of HDAC10, the Cytosolic Polyamine Deacetylase. Acs Chem.Biol., 15:2154-2163, 2020 Cited by PubMed: 32659072DOI: 10.1021/acschembio.0c00362 PDB entries with the same primary citation |
Experimental method |
Structure validation
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