6WCR

Crystal structure of the A/Puerto Rico/8/1934 (H1N1) influenza virus hemagglutinin in complex with small molecule F0045(S)

6WCR の概要

• エントリーDOI: 10.2210/pdb6wcr/pdb
• 分子名称: Hemagglutinin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: hemagglutinin, fusion inhibitors, small molecules, antiviral protein
• 由来する生物種: Influenza A virus (strain A/Puerto Rico/8/1934 H1N1); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 58578.26

構造登録者

kadam, R.U.,Wilson, I.A. (登録日: 2020-03-31, 公開日: 2020-08-05, 最終更新日: 2023-10-18)

• 主引用文献: Yao, Y.,Kadam, R.U.,Lee, C.D.,Woehl, J.L.,Wu, N.C.,Zhu, X.,Kitamura, S.,Wilson, I.A.,Wolan, D.W.; An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen.; Proc.Natl.Acad.Sci.USA, 117:18431-18438, 2020; PubMed: 32690700; DOI: 10.1073/pnas.2006893117

実験手法

X-RAY DIFFRACTION (2.68 Å)