6WBC
Structure of Mouse Importin alpha- MLH1-R472K NLS Peptide Complex
Summary for 6WBC
Entry DOI | 10.2210/pdb6wbc/pdb |
Descriptor | Importin subunit alpha-1, DNA mismatch repair protein Mlh1 (3 entities in total) |
Functional Keywords | importin alpha, nuclear import, nls, mlh1, protein transport, protein transport-nuclear protein complex, protein transport/nuclear protein |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 51245.12 |
Authors | de Barros, A.C.,da Silva, T.D.,Oliveira, H.C.,Fukuda, C.A.,Fontes, M.R.M. (deposition date: 2020-03-26, release date: 2021-07-07, Last modification date: 2023-10-18) |
Primary citation | de Oliveira, H.C.,da Silva, T.D.,Salvador, G.H.M.,Moraes, I.R.,Fukuda, C.A.,de Barros, A.C.,Fontes, M.R.M. Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha. Biochem.J., 478:2715-2732, 2021 Cited by PubMed: 34195786DOI: 10.1042/BCJ20210401 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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