6W9U
Structure of human MAIT A-F7 TCR in complex with patient MR1-R9H-Ac-6-FP
Summary for 6W9U
Entry DOI | 10.2210/pdb6w9u/pdb |
Descriptor | Major histocompatibility complex class I-related gene protein, Beta-2-microglobulin, TCR-alpha chain, ... (8 entities in total) |
Functional Keywords | immune system, mait, mr1, metabolite |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 188960.26 |
Authors | Awad, W.,Rossjohn, J. (deposition date: 2020-03-23, release date: 2020-08-05, Last modification date: 2023-10-18) |
Primary citation | Howson, L.J.,Awad, W.,von Borstel, A.,Lim, H.J.,McWilliam, H.E.G.,Sandoval-Romero, M.L.,Majumdar, S.,Hamzeh, A.R.,Andrews, T.D.,McDermott, D.H.,Murphy, P.M.,Le Nours, J.,Mak, J.Y.W.,Liu, L.,Fairlie, D.P.,McCluskey, J.,Villadangos, J.A.,Cook, M.C.,Turner, S.J.,Davey, M.S.,Ojaimi, S.,Rossjohn, J. Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1 . Sci Immunol, 5:-, 2020 Cited by PubMed: 32709702DOI: 10.1126/sciimmunol.abc9492 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
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