6W52
Prefusion RSV F bound by neutralizing antibody RSB1
Summary for 6W52
| Entry DOI | 10.2210/pdb6w52/pdb |
| Descriptor | Fusion glycoprotein F0, Fusion glycoprotein F1 fused with Fibritin trimerization domain, RSB1 Fab Heavy Chain, ... (4 entities in total) |
| Functional Keywords | rsv, antibody, neutralization, prefusion, vaccine, viral protein |
| Biological source | Human respiratory syncytial virus A (strain A2) More |
| Total number of polymer chains | 4 |
| Total formula weight | 109939.02 |
| Authors | Harshbarger, W.,Chandramouli, S.,Malito, M. (deposition date: 2020-03-12, release date: 2020-11-11, Last modification date: 2023-10-18) |
| Primary citation | Harshbarger, W.,Tian, S.,Wahome, N.,Balsaraf, A.,Bhattacharya, D.,Jiang, D.,Pandey, R.,Tungare, K.,Friedrich, K.,Mehzabeen, N.,Biancucci, M.,Chinchilla-Olszar, D.,Mallett, C.P.,Huang, Y.,Wang, Z.,Bottomley, M.J.,Malito, E.,Chandramouli, S. Convergent structural features of respiratory syncytial virus neutralizing antibodies and plasticity of the site V epitope on prefusion F. Plos Pathog., 16:e1008943-e1008943, 2020 Cited by PubMed: 33137810DOI: 10.1371/journal.ppat.1008943 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.74 Å) |
Structure validation
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