6W52

Prefusion RSV F bound by neutralizing antibody RSB1

6W52 の概要

• エントリーDOI: 10.2210/pdb6w52/pdb
• 分子名称: Fusion glycoprotein F0, Fusion glycoprotein F1 fused with Fibritin trimerization domain, RSB1 Fab Heavy Chain, ... (4 entities in total)
• 機能のキーワード: rsv, antibody, neutralization, prefusion, vaccine, viral protein
• 由来する生物種: Human respiratory syncytial virus A (strain A2); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 109939.02

構造登録者

Harshbarger, W.,Chandramouli, S.,Malito, M. (登録日: 2020-03-12, 公開日: 2020-11-11, 最終更新日: 2023-10-18)

• 主引用文献: Harshbarger, W.,Tian, S.,Wahome, N.,Balsaraf, A.,Bhattacharya, D.,Jiang, D.,Pandey, R.,Tungare, K.,Friedrich, K.,Mehzabeen, N.,Biancucci, M.,Chinchilla-Olszar, D.,Mallett, C.P.,Huang, Y.,Wang, Z.,Bottomley, M.J.,Malito, E.,Chandramouli, S.; Convergent structural features of respiratory syncytial virus neutralizing antibodies and plasticity of the site V epitope on prefusion F.; Plos Pathog., 16:e1008943-e1008943, 2020; PubMed: 33137810; DOI: 10.1371/journal.ppat.1008943

実験手法

X-RAY DIFFRACTION (3.74 Å)