6W30
Protein Tyrosine Phosphatase 1B Bound to Amorphadiene
Summary for 6W30
Entry DOI | 10.2210/pdb6w30/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 1, GLYCEROL, Amorphadiene, ... (5 entities in total) |
Functional Keywords | ptp1b, allosteric inhibitor, terpenoid, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 38757.53 |
Authors | Sarkar, A.,Kim, E.Y.,Hongdusit, A.,Sankaran, B.,Fox, J. (deposition date: 2020-03-08, release date: 2021-05-26, Last modification date: 2023-10-18) |
Primary citation | Sarkar, A.,Kim, E.Y.,Jang, T.,Hongdusit, A.,Kim, H.,Choi, J.M.,Fox, J.M. Microbially Guided Discovery and Biosynthesis of Biologically Active Natural Products. Acs Synth Biol, 10:1505-1519, 2021 Cited by PubMed: 33988973DOI: 10.1021/acssynbio.1c00074 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report