6VY2

Cryo-EM structure of M1214_N1 Fab in complex with CH505 TF chimeric SOSIP.664 Env trimer

6VY2 の概要

• エントリーDOI: 10.2210/pdb6vy2/pdb
• EMDBエントリー: 21456
• 分子名称: Glycoprotein 120, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• 機能のキーワード: cryo-em, broadly neutralizing antibody, bnab, fab, human immunodeficiency virus, hiv-1, ch505, sosip, env, immune system
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 394729.68

構造登録者

Chan, K.-W.,Kong, X.P. (登録日: 2020-02-25, 公開日: 2020-05-06, 最終更新日: 2020-07-29)

• 主引用文献: Jia, M.,Liberatore, R.A.,Guo, Y.,Chan, K.W.,Pan, R.,Lu, H.,Waltari, E.,Mittler, E.,Chandran, K.,Finzi, A.,Kaufmann, D.E.,Seaman, M.S.,Ho, D.D.,Shapiro, L.,Sheng, Z.,Kong, X.P.,Bieniasz, P.D.,Wu, X.; VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA.; Cell Host Microbe, 27:963-, 2020; PubMed: 32315598; DOI: 10.1016/j.chom.2020.03.024

実験手法

ELECTRON MICROSCOPY (4.86 Å)