6VU5

Structure of G-alpha-q bound to its chaperone Ric-8A

6VU5 の概要

• エントリーDOI: 10.2210/pdb6vu5/pdb
• EMDBエントリー: 21387
• 分子名称: Resistance to inhibitors of cholinesterase-8A (Ric-8A), Guanine nucleotide-binding protein G(q) subunit alpha (2 entities in total)
• 機能のキーワード: g protein alpha subunit, ric-8; molecular chaperone; g alpha folding; guanine nucleotide exchange factor (gef); cryoem structure; protein complex; g protein-coupled receptor (gpcr), phosphorylation; quality control., chaperone
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 96105.92

構造登録者

Seven, A.B.,Hilger, D. (登録日: 2020-02-14, 公開日: 2020-03-18, 最終更新日: 2020-03-25)

• 主引用文献: Seven, A.B.,Hilger, D.,Papasergi-Scott, M.M.,Zhang, L.,Qu, Q.,Kobilka, B.K.,Tall, G.G.,Skiniotis, G.; Structures of G alpha Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms.; Cell Rep, 30:3699-3709.e6, 2020; PubMed: 32126208; DOI: 10.1016/j.celrep.2020.02.086

実験手法

ELECTRON MICROSCOPY (3.5 Å)