6VTE

Naegleria gruberi RNA Ligase K170M mutant with AMP and Mn

6VTE の概要

• エントリーDOI: 10.2210/pdb6vte/pdb
• 分子名称: RNA ligase, ADENOSINE MONOPHOSPHATE, MANGANESE (II) ION, ... (4 entities in total)
• 機能のキーワード: rna repair, adenylyltransferase, ligase
• 由来する生物種: Naegleria gruberi (Amoeba)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39066.01

構造登録者

Unciuleac, M.C.,Goldgur, Y.,Shuman, S. (登録日: 2020-02-12, 公開日: 2020-04-08, 最終更新日: 2023-10-11)

• 主引用文献: Unciuleac, M.C.,Goldgur, Y.,Shuman, S.; Caveat mutator: alanine substitutions for conserved amino acids in RNA ligase elicit unexpected rearrangements of the active site for lysine adenylylation.; Nucleic Acids Res., 48:5603-5615, 2020; PubMed: 32315072; DOI: 10.1093/nar/gkaa238

実験手法

X-RAY DIFFRACTION (2.1 Å)