6VQO
T cell receptor-p53-HLA-A2 complex
Summary for 6VQO
Entry DOI | 10.2210/pdb6vqo/pdb |
Descriptor | MHC class I antigen, Beta-2-microglobulin, T-cell receptor 1a2, alfa chain, ... (5 entities in total) |
Functional Keywords | tcr complex, mhc, hla, adoptive cell therapy, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 10 |
Total formula weight | 196152.20 |
Authors | Wu, D.,Gallagher, D.T.,Pierce, B.G.,Mariuzza, R.A. (deposition date: 2020-02-05, release date: 2020-06-17, Last modification date: 2023-10-11) |
Primary citation | Wu, D.,Gallagher, D.T.,Gowthaman, R.,Pierce, B.G.,Mariuzza, R.A. Structural basis for oligoclonal T cell recognition of a shared p53 cancer neoantigen. Nat Commun, 11:2908-2908, 2020 Cited by PubMed: 32518267DOI: 10.1038/s41467-020-16755-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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