6VPX

Nanodisc of full-length HIV-1 Envelope glycoprotein clone AMC011 in complex with one PGT151 Fab and three 10E8 Fabs

6VPX の概要

• エントリーDOI: 10.2210/pdb6vpx/pdb
• EMDBエントリー: 21335
• 分子名称: Envelope glycoprotein gp120, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (18 entities in total)
• 機能のキーワード: hiv, envelope glycoprotein, env, neutralizing antibody, nanodisc, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 17
• 化学式量合計: 343307.12

構造登録者

Rantalainen, K.,Ward, A.B.W. (登録日: 2020-02-04, 公開日: 2020-04-22, 最終更新日: 2020-07-29)

• 主引用文献: Rantalainen, K.,Berndsen, Z.T.,Antanasijevic, A.,Schiffner, T.,Zhang, X.,Lee, W.H.,Torres, J.L.,Zhang, L.,Irimia, A.,Copps, J.,Zhou, K.H.,Kwon, Y.D.,Law, W.H.,Schramm, C.A.,Verardi, R.,Krebs, S.J.,Kwong, P.D.,Doria-Rose, N.A.,Wilson, I.A.,Zwick, M.B.,Yates 3rd, J.R.,Schief, W.R.,Ward, A.B.; HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies.; Cell Rep, 31:107583-107583, 2020; PubMed: 32348769; DOI: 10.1016/j.celrep.2020.107583

実験手法

ELECTRON MICROSCOPY (5 Å)