6VPS

Cryo-EM structure of the amyloid core of Drosophila Orb2 isolated from head

Summary for 6VPS

• Entry DOI: 10.2210/pdb6vps/pdb
• EMDB information: 21316
• Descriptor: Translational regulator orb2 (1 entity in total)
• Functional Keywords: amyloid, prion-like, long-term memory, protein fibril
• Biological source: Drosophila melanogaster (Fruit fly)
• Total number of polymer chains: 9
• Total formula weight: 35767.53

Authors

Hervas, R.,Rau, M.J.,Park, Y.,Zhang, W.,Murzin, A.G.,Fitzpatrick, J.A.J.,Scheres, S.H.W.,Si, K. (deposition date: 2020-02-04, release date: 2020-03-18, Last modification date: 2024-03-06)

• Primary citation: Hervas, R.,Rau, M.J.,Park, Y.,Zhang, W.,Murzin, A.G.,Fitzpatrick, J.A.J.,Scheres, S.H.W.,Si, K.; Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila; Science, 367:1230-1234, 2020; DOI: 10.1126/science.aba3526

Experimental method

ELECTRON MICROSCOPY (2.6 Å)