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6VNT

Tryptophan synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, aminoacrylate at the beta site, and sodium ion at the metal coordination site at 1.25 Angstrom resolution

Summary for 6VNT
Entry DOI10.2210/pdb6vnt/pdb
Related4HN4 4HPX 6D0V 6DUC
DescriptorTryptophan synthase alpha chain, Tryptophan synthase beta chain, 1,2-ETHANEDIOL, ... (8 entities in total)
Functional Keywordsprotein complex, lyase, salmonella, lyase-lyase inhibitor complex, lyase/lyase inhibitor
Biological sourceSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
More
Total number of polymer chains2
Total formula weight72844.67
Authors
Hilario, E.,Fan, L.,Dunn, M.F.,Mueller, L.J. (deposition date: 2020-01-29, release date: 2021-02-03, Last modification date: 2023-10-11)
Primary citationHilario, E.,Fan, L.,Dunn, M.F.,Mueller, L.J.
Tryptophan synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, aminoacrylate at the beta site, and sodium ion at the metal coordination site at 1.25 Angstrom resolution.
To be Published,
Experimental method
X-RAY DIFFRACTION (1.25 Å)
Structure validation

226707

数据于2024-10-30公开中

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