6VNT
Tryptophan synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, aminoacrylate at the beta site, and sodium ion at the metal coordination site at 1.25 Angstrom resolution
Summary for 6VNT
Entry DOI | 10.2210/pdb6vnt/pdb |
Related | 4HN4 4HPX 6D0V 6DUC |
Descriptor | Tryptophan synthase alpha chain, Tryptophan synthase beta chain, 1,2-ETHANEDIOL, ... (8 entities in total) |
Functional Keywords | protein complex, lyase, salmonella, lyase-lyase inhibitor complex, lyase/lyase inhibitor |
Biological source | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) More |
Total number of polymer chains | 2 |
Total formula weight | 72844.67 |
Authors | Hilario, E.,Fan, L.,Dunn, M.F.,Mueller, L.J. (deposition date: 2020-01-29, release date: 2021-02-03, Last modification date: 2023-10-11) |
Primary citation | Hilario, E.,Fan, L.,Dunn, M.F.,Mueller, L.J. Tryptophan synthase in complex with inhibitor N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the alpha-site, aminoacrylate at the beta site, and sodium ion at the metal coordination site at 1.25 Angstrom resolution. To be Published, |
Experimental method | X-RAY DIFFRACTION (1.25 Å) |
Structure validation
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