6VN1
A 2.8 Angstrom Cryo-EM Structure of a Glycoprotein B-Neutralizing Antibody Complex Reveals a Critical Domain for Herpesvirus Fusion Initiation
Summary for 6VN1
Entry DOI | 10.2210/pdb6vn1/pdb |
EMDB information | 21247 |
Descriptor | Human monoclonal antibody 93k variable light chain, Human monoclonal antibody 93k variable heavy chain, Envelope glycoprotein B (3 entities in total) |
Functional Keywords | varicella zoster virus, glycoprotein b, neutralization, monoclonal antibody, viral protein-immune system complex, viral protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 9 |
Total formula weight | 392960.77 |
Authors | Oliver, S.L. (deposition date: 2020-01-29, release date: 2020-07-15, Last modification date: 2020-09-02) |
Primary citation | Oliver, S.L.,Xing, Y.,Chen, D.H.,Roh, S.H.,Pintilie, G.D.,Bushnell, D.A.,Sommer, M.H.,Yang, E.,Carfi, A.,Chiu, W.,Arvin, A.M. A glycoprotein B-neutralizing antibody structure at 2.8 angstrom uncovers a critical domain for herpesvirus fusion initiation. Nat Commun, 11:4141-4141, 2020 Cited by PubMed: 32811830DOI: 10.1038/s41467-020-17911-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.8 Å) |
Structure validation
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