6VMX

Structure of HD14 TCR in complex with HLA-B7 presenting an EBV epitope

Summary for 6VMX

• Entry DOI: 10.2210/pdb6vmx/pdb
• Descriptor: HLA class I histocompatibility antigen, B-7 alpha chain, Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, ... (8 entities in total)
• Functional Keywords: tcr, mhc, ebv, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 191264.67

Authors

Farenc, C.,Rossjohn, J.,Gras, S. (deposition date: 2020-01-28, release date: 2020-07-29, Last modification date: 2023-10-11)

• Primary citation: Rowntree, L.C.,Nguyen, T.H.O.,Farenc, C.,Halim, H.,Hensen, L.,Rossjohn, J.,Kotsimbos, T.C.,Purcell, A.W.,Kedzierska, K.,Gras, S.,Mifsud, N.A.; A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals.; J Immunol., 205:1524-1534, 2020; PubMed: 32817371; DOI: 10.4049/jimmunol.2000249

Experimental method

X-RAY DIFFRACTION (3.1 Å)