6VK0

CryoEM structure of Hrd1-Usa1/Der1/Hrd3 of the flipped topology

6VK0 の概要

• エントリーDOI: 10.2210/pdb6vk0/pdb
• EMDBエントリー: 21220 21221 21222
• 分子名称: U1 SNP1-associating protein 1, Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... (4 entities in total)
• 機能のキーワード: retro-translocation, erad, protein degradation, ubiquitination, protein transport
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 208233.89

構造登録者

Wu, X.,Rapoport, T.A. (登録日: 2020-01-18, 公開日: 2020-04-29, 最終更新日: 2024-03-06)

• 主引用文献: Wu, X.,Siggel, M.,Ovchinnikov, S.,Mi, W.,Svetlov, V.,Nudler, E.,Liao, M.,Hummer, G.,Rapoport, T.A.; Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex.; Science, 368:-, 2020; PubMed: 32327568; DOI: 10.1126/science.aaz2449

実験手法

ELECTRON MICROSCOPY (4.1 Å)