6VJT
Co-crystals of broadly neutralizing antibody with the linear epitope from Hepatitis B surface antigen
Summary for 6VJT
Entry DOI | 10.2210/pdb6vjt/pdb |
Descriptor | Heavy Chain Fab Fragment of Monoclonal Ab15, Light Chain Fab Fragment of Monoclonal antibody A15, antigenic region 139-148 of Hepatitis B surface antigen protein, ... (4 entities in total) |
Functional Keywords | hepatitis b, hepb, fab, ab, antibody, antiviral protein, antiviral protein-immune system complex, antiviral protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 48416.87 |
Authors | Oren, D.A.,Nussenzweig, M.C.,Wang, Q. (deposition date: 2020-01-17, release date: 2020-08-26, Last modification date: 2023-10-11) |
Primary citation | Wang, Q.,Michailidis, E.,Yu, Y.,Wang, Z.,Hurley, A.M.,Oren, D.A.,Mayer, C.T.,Gazumyan, A.,Liu, Z.,Zhou, Y.,Schoofs, T.,Yao, K.H.,Nieke, J.P.,Wu, J.,Jiang, Q.,Zou, C.,Kabbani, M.,Quirk, C.,Oliveira, T.,Chhosphel, K.,Zhang, Q.,Schneider, W.M.,Jahan, C.,Ying, T.,Horowitz, J.,Caskey, M.,Jankovic, M.,Robbiani, D.F.,Wen, Y.,de Jong, Y.P.,Rice, C.M.,Nussenzweig, M.C. A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations. Cell Host Microbe, 28:335-349.e6, 2020 Cited by PubMed: 32504577DOI: 10.1016/j.chom.2020.05.010 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.782 Å) |
Structure validation
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