6VJT
Co-crystals of broadly neutralizing antibody with the linear epitope from Hepatitis B surface antigen
6VJT の概要
エントリーDOI | 10.2210/pdb6vjt/pdb |
分子名称 | Heavy Chain Fab Fragment of Monoclonal Ab15, Light Chain Fab Fragment of Monoclonal antibody A15, antigenic region 139-148 of Hepatitis B surface antigen protein, ... (4 entities in total) |
機能のキーワード | hepatitis b, hepb, fab, ab, antibody, antiviral protein, antiviral protein-immune system complex, antiviral protein/immune system |
由来する生物種 | Homo sapiens (Human) 詳細 |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 48416.87 |
構造登録者 | |
主引用文献 | Wang, Q.,Michailidis, E.,Yu, Y.,Wang, Z.,Hurley, A.M.,Oren, D.A.,Mayer, C.T.,Gazumyan, A.,Liu, Z.,Zhou, Y.,Schoofs, T.,Yao, K.H.,Nieke, J.P.,Wu, J.,Jiang, Q.,Zou, C.,Kabbani, M.,Quirk, C.,Oliveira, T.,Chhosphel, K.,Zhang, Q.,Schneider, W.M.,Jahan, C.,Ying, T.,Horowitz, J.,Caskey, M.,Jankovic, M.,Robbiani, D.F.,Wen, Y.,de Jong, Y.P.,Rice, C.M.,Nussenzweig, M.C. A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations. Cell Host Microbe, 28:335-349.e6, 2020 Cited by PubMed: 32504577DOI: 10.1016/j.chom.2020.05.010 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.782 Å) |
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