6VJT

Co-crystals of broadly neutralizing antibody with the linear epitope from Hepatitis B surface antigen

6VJT の概要

• エントリーDOI: 10.2210/pdb6vjt/pdb
• 分子名称: Heavy Chain Fab Fragment of Monoclonal Ab15, Light Chain Fab Fragment of Monoclonal antibody A15, antigenic region 139-148 of Hepatitis B surface antigen protein, ... (4 entities in total)
• 機能のキーワード: hepatitis b, hepb, fab, ab, antibody, antiviral protein, antiviral protein-immune system complex, antiviral protein/immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 48416.87

構造登録者

Oren, D.A.,Nussenzweig, M.C.,Wang, Q. (登録日: 2020-01-17, 公開日: 2020-08-26, 最終更新日: 2023-10-11)

• 主引用文献: Wang, Q.,Michailidis, E.,Yu, Y.,Wang, Z.,Hurley, A.M.,Oren, D.A.,Mayer, C.T.,Gazumyan, A.,Liu, Z.,Zhou, Y.,Schoofs, T.,Yao, K.H.,Nieke, J.P.,Wu, J.,Jiang, Q.,Zou, C.,Kabbani, M.,Quirk, C.,Oliveira, T.,Chhosphel, K.,Zhang, Q.,Schneider, W.M.,Jahan, C.,Ying, T.,Horowitz, J.,Caskey, M.,Jankovic, M.,Robbiani, D.F.,Wen, Y.,de Jong, Y.P.,Rice, C.M.,Nussenzweig, M.C.; A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations.; Cell Host Microbe, 28:335-349.e6, 2020; PubMed: 32504577; DOI: 10.1016/j.chom.2020.05.010

実験手法

X-RAY DIFFRACTION (1.782 Å)