6VJC
LmFPPS mutant T164Y in complex with 476A, IPP & Ca
Summary for 6VJC
Entry DOI | 10.2210/pdb6vjc/pdb |
Descriptor | Farnesyl pyrophosphate synthase, CALCIUM ION, ISOPENTYL PYROPHOSPHATE, ... (7 entities in total) |
Functional Keywords | fpps, farnesyl diphosphate synthase, isoprenoid, transferase |
Biological source | Leishmania major |
Total number of polymer chains | 2 |
Total formula weight | 83823.89 |
Authors | Maheshwari, S.,Kim, Y.S.,Aripirala, S.,Gabelli, S.B. (deposition date: 2020-01-15, release date: 2020-11-25, Last modification date: 2023-10-11) |
Primary citation | Maheshwari, S.,Kim, Y.S.,Aripirala, S.,Murphy, M.,Amzel, L.M.,Gabelli, S.B. Identifying Structural Determinants of Product Specificity in Leishmania major Farnesyl Diphosphate Synthase. Biochemistry, 59:2751-2759, 2020 Cited by PubMed: 32584028DOI: 10.1021/acs.biochem.0c00432 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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