6VI9

Observing a ring-cleaving dioxygenase in action through a crystalline lens - an alkylperoxo bound structure

6VI9 の概要

• エントリーDOI: 10.2210/pdb6vi9/pdb
• 分子名称: 3-hydroxyanthranilate 3,4-dioxygenase, FE (II) ION, (5R,6Z)-5-(hydroperoxy-kappaO)-5-(hydroxy-kappaO)-6-iminocyclohexa-1,3-diene-1-carboxylato(2-)iron, ... (5 entities in total)
• 機能のキーワード: in crystallo reaction, extradiol dioxygenase, nad+ biosynthesis, intermediate, oxidoreductase
• 由来する生物種: Cupriavidus metallidurans (strain ATCC 43123 / DSM 2839 / NBRC 102507 / CH34)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23006.32

構造登録者

Wang, Y.,Liu, F.,Yang, Y.,Liu, A. (登録日: 2020-01-12, 公開日: 2020-07-29, 最終更新日: 2023-10-11)

• 主引用文献: Wang, Y.,Liu, K.F.,Yang, Y.,Davis, I.,Liu, A.; Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens.; Proc.Natl.Acad.Sci.USA, 117:19720-19730, 2020; PubMed: 32732435; DOI: 10.1073/pnas.2005327117

実験手法

X-RAY DIFFRACTION (2.31 Å)